@font-face {
  font-family: 'OptiMod Inter';
  src: url('assets/fonts/inter-latin.woff2') format('woff2');
  font-style: normal;
  font-weight: 100 900;
  font-display: swap;
}

:root {
  --sans: 'OptiMod Inter', Inter, -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
  --ink: #1b2622;
  --muted: #58665f;
  --paper: #f6f6f0;
  --dark: #14221c;
  --line: #d7ded4;
  --motion-ease: cubic-bezier(.22,.68,.22,1);
  --rail: clamp(22px, 4.8vw, 72px);
  --section-space: clamp(58px, 6.5vw, 100px);
}

body { font-optical-sizing: auto; }
.wrap { width: min(1220px, calc(100% - 2 * var(--rail))); }
.section { padding-block: var(--section-space); }
:is(h1,h2,h3) { text-wrap: balance; }
h1,h2 { letter-spacing: -.058em; }
h3 { letter-spacing: -.035em; }
h2 { font-size: clamp(35px, 3.7vw, 55px); line-height: 1.075; }
.section-head { gap: clamp(30px, 4vw, 68px); margin-bottom: clamp(30px, 3.5vw, 51px); }
.section-head > p { max-width: 38ch; font-size: 15px; line-height: 1.75; }
.eyebrow { margin-bottom: 22px; font-size: 10px; letter-spacing: .11em; }
.button,.text-link { font-family: var(--sans); }
.button { min-height: 46px; border-radius: 5px; gap: 20px; padding: 12px 18px; font-size: 13px; font-weight: 570; transition: background-color 160ms, border-color 160ms, color 160ms; }
.button:hover { transform: none; }
.text-link { gap: 11px; font-weight: 500; }
.button .ui-arrow,.text-link .ui-arrow,.report-open .ui-arrow,.finding-report-link .ui-arrow { transition: transform 175ms var(--motion-ease); }
@media (hover: hover) and (pointer: fine) {
  :is(.button,.text-link,.report-open,.finding-report-link):hover .ui-arrow { transform: translate(2px,-2px); }
}

/* Navigation stays in the same column as the page content on large displays. */
.site-header { height: 76px; background: #f8f8f3; }
.header-inner { gap: 25px; }
.logo { width: 139px; height: 42px; }
.nav { gap: clamp(15px, 2vw, 27px); font-size: 12px; }
.nav > a:not(.button) { white-space: nowrap; }
.nav > a:not(.button)::after { content: ''; position: absolute; left: 0; right: 0; bottom: -7px; height: 1px; background: currentColor; transform: scaleX(0); transform-origin: left; transition: transform 160ms var(--motion-ease); }
.nav > a:not(.button):is(:hover,[aria-current=page])::after { height: 1px; bottom: -7px; transform: scaleX(1); }
.nav .button { min-height: 40px; font-size: 12px; gap: 14px; }
.menu-button { border-radius: 5px; }
.menu-glyph { width: 17px; height: 15px; display: inline-flex; flex-direction: column; justify-content: center; gap: 4px; vertical-align: middle; margin-left: 7px; }
.menu-glyph i { display: block; height: 1px; width: 15px; background: currentColor; transition: transform 180ms var(--motion-ease); }
.menu-button[aria-expanded=true] i:first-child { transform: translateY(2.5px) rotate(45deg); }
.menu-button[aria-expanded=true] i:last-child { transform: translateY(-2.5px) rotate(-45deg); }
.return-home { display: inline-flex; align-items: center; gap: 9px; min-height: 28px; }
.return-home .ui-arrow { width: 18px; height: 18px; transition: transform 180ms var(--motion-ease); }
.faq summary::after { content: ''; display: block; width: 20px; height: 24px; flex: none; background: linear-gradient(currentColor,currentColor) center / 12px 1px no-repeat, linear-gradient(currentColor,currentColor) center / 1px 12px no-repeat; transition: transform 200ms var(--motion-ease); }
.faq[open] summary::after { content: ''; transform: rotate(45deg); }

/* The main finding is a real estimate from the downloadable example. */
.hero { background: radial-gradient(ellipse at 84% 64%, #25382a 0, #17271e 32%, #14221c 64%); }
.hero::after { display: none; }
.hero-grid { grid-template-columns: minmax(0,1.02fr) minmax(0,.98fr); gap: clamp(36px,6vw,80px); padding-block: clamp(70px,6.8vw,108px); }
.hero h1 { font-size: clamp(56px,5.55vw,84px); line-height: 1.025; letter-spacing: -.055em; font-weight: 465; }
.hero-copy > p { max-width: 46ch; font-size: clamp(16px,1.12vw,18px); line-height: 1.75; margin-top: 26px; color: #bfcbc2; }
.hero .eyebrow { color: #c9d2c8; max-width: 440px; }
.hero-footnote { font-size: 11px; color: #b5c3b8; }
.finding-window { position: relative; z-index: 1; width: 100%; max-width: 520px; justify-self: end; background: #fcfdf9; color: #23362a; border: 1px solid #d6dfd1; border-radius: 14px; overflow: hidden; box-shadow: 0 24px 66px #07180a30; }
.finding-window-bar { display: flex; align-items: center; gap: 18px; min-height: 43px; padding: 8px 17px; border-bottom: 1px solid #dbe1d6; background: #edf1e8; font-size: 11px; font-weight: 520; color: #526650; }
.finding-window-bar > img { margin-left: auto; width: 18px; height: 18px; }
.window-divider { margin: 0 6px; color: #99a591; }
.finding-window-bar .window-dots { display: flex; gap: 5px; }
.finding-window-bar .window-dots i { width: 6px; height: 6px; background: #bac5b3; border-radius: 50%; }
.finding-window-body { padding: clamp(22px,2.45vw,35px) clamp(22px,2.8vw,39px) 22px; }
.finding-context { display: flex; justify-content: space-between; align-items: baseline; gap: 8px 14px; flex-wrap: wrap; font-size: 11px; line-height: 1.6; color: #687761; }
.finding-context > span:first-child { color: #374a37; font-weight: 600; }
.finding-window h2 { color: #263a2b; font-size: clamp(33px,3.15vw,49px); line-height: 1.02; letter-spacing: -.058em; margin: 22px 0 12px; }
.finding-window h2 strong { font-weight: 590; }
.finding-window-body > p { font-size: 13px; line-height: 1.65; color: #53644f; max-width: 37ch; }
.finding-interval { border-top: 1px solid #dce4d7; padding-top: 16px; margin-top: 22px; }
.finding-interval figcaption { color: #4e6149; font-size: 12px; font-weight: 540; }
.finding-interval svg { width: 100%; height: auto; margin-top: 3px; }
.finding-interval p { display: flex; align-items: center; gap: 8px; color: #52644c; font-size: 11px; font-variant-numeric: tabular-nums; }
.finding-interval i { display: inline-block; width: 14px; height: 3px; background: #91a770; }
.finding-report-link { display: flex; align-items: center; justify-content: space-between; gap: 20px; padding: 14px clamp(22px,2.8vw,39px); background: #f1f5eb; border-top: 1px solid #dce4d7; font-size: 12px; font-weight: 570; }
.finding-report-link small { display: block; color: #62745a; font-size: 10px; font-weight: 440; margin-bottom: 2px; }
.finding-report-link:hover { background: #e9efdf; }

/* The network marks stay at their approved proportions. */
.network-band { padding-block: 28px 25px; }
.network-heading { margin-bottom: 21px; }
.network-heading .kicker { letter-spacing: .09em; }
.network-logo { gap: 15px; }
.network-logo:hover img { transform: none; }
.analysis-introduction .split { grid-template-columns: minmax(0,1.04fr) minmax(0,.96fr); gap: clamp(50px,7vw,102px); align-items: start; }
.analysis-introduction .problem-copy > p { max-width: 50ch; font-size: 15px; line-height: 1.78; margin-top: 18px; }
.analysis-introduction .problem-copy .lead { font-size: 18px; color: #35493c; margin-top: 25px; }
.challenge-list { padding-top: 4px; margin: 0; }
.challenge-item { padding: 24px 0; gap: 12px; grid-template-columns: 33px minmax(0,1fr); }
.challenge-item .index { font-size: 10px; }
.challenge-item h3 { font-size: 23px; }
.challenge-item p { font-size: 14px; line-height: 1.75; max-width: 48ch; }
.problem-copy .note { line-height: 1.7; color: #56674f; max-width: 54ch; }
.problem-copy .note .text-link { display: table; margin-top: 9px; font-size: 12px; }
#method { background: #e9eee3; }
.method-grid { position: relative; gap: clamp(18px,2.3vw,34px); }
.method-card { border-top: 1px solid #b6c4ac; padding-top: 18px; }
.method-card .number { align-items: center; }
.method-card .number .method-step-number { font: 11px var(--mono); color: #64785a; }
.method-drawing { height: 25px; width: 35px; color: #617455; }
.method-card h3 { margin-top: 27px; font-size: 24px; line-height: 1.15; }
.method-card p { font-size: 14px; line-height: 1.75; }
.method-foot { align-items: center; margin-top: 31px; }
.method-foot .text-link { font-size: 12px; }
.standard-intro { max-width: 748px; font-size: 17px; line-height: 1.78; }
.replication-context { border-left-color: #abb99b; }
.replication-context > strong { font-variant-numeric: tabular-nums; letter-spacing: -.07em; }
.rigour-grid { gap: clamp(25px,3vw,48px); }
.rigour-grid h3 { font-size: 27px; }
.rigour-grid p { font-size: 14px; line-height: 1.77; }
.hybrid-brief { margin-top: 50px; padding-top: 34px; }
.hybrid-brief h3 { font-size: 32px; }
.hybrid-roles p { line-height: 1.72; }
.focus-tour { background: #f0f3ed; }
.focus-tour .section-head :is(h1,h2) { font-size: clamp(36px,3.8vw,56px); }
.ft-app { box-shadow: 0 14px 42px #1b302013, 0 2px 6px #1b302007; }
.tour-bottom > p { line-height: 1.7; }

/* A full-size, unaltered report cover gives the document a tangible presence. */
.report-edition { background: #fff; }
.report-composition { display: grid; grid-template-columns: minmax(0,1.12fr) minmax(0,.88fr); gap: clamp(44px,6vw,92px); align-items: center; }
.report-copy h2 { font-size: clamp(37px,3.8vw,54px); }
.report-copy .report-intro { max-width: 51ch; font-size: 16px; line-height: 1.75; }
.report-contents { margin: 28px 0 0; }
.report-contents > div { display: grid; grid-template-columns: 115px minmax(0,1fr); gap: 16px; border-top: 1px solid var(--line); padding: 15px 0; }
.report-contents dt { font-size: 13px; font-weight: 580; color: #263b2b; }
.report-contents dd { margin: 0; color: var(--muted); font-size: 13px; line-height: 1.75; }
.report-resources { margin-top: 22px; }
.report-resources .text-link { font-size: 12px; }
.report-resources p { margin-top: 10px; font-size: 12px; line-height: 1.6; }
.report-display { padding: clamp(23px,2.5vw,37px) clamp(24px,3vw,46px) 20px; background: #e9eee3; border: 1px solid #d9e1d1; border-radius: 8px; }
.report-thumbnail { display: block; width: min(100%,265px); margin: auto; box-shadow: 2px 3px 0 #cfd8c6, 0 10px 27px #253b2520; }
.report-thumbnail img { width: 100%; height: auto; }
.report-display figcaption { display: flex; justify-content: space-between; align-items: center; gap: 15px; margin-top: 23px; border-top: 1px solid #cbd6c3; padding-top: 15px; }
.report-display figcaption strong,.report-display figcaption small { display: block; }
.report-display figcaption strong { font-size: 13px; font-weight: 560; }
.report-display figcaption small { font-size: 10px; color: #53654c; line-height: 1.65; margin-top: 4px; }
.report-open { display: inline-flex; align-items: center; gap: 6px; white-space: nowrap; color: #263e2c; font-size: 12px; border-bottom: 1px solid #889b7b; }

/* Questions and their decision context share one reading plane. */
.applications { background: #17271e; }
.use-layout { grid-template-columns: minmax(205px,.55fr) minmax(0,1.45fr); align-items: start; gap: clamp(36px,5.2vw,80px); }
.use-button { gap: 12px; align-items: center; padding: 16px 0; font-size: 15px; min-height: 48px; color: #bdc8bf; }
.use-button:last-child { border-bottom: 0; }
.use-button span { opacity: .4; }
.use-button[aria-selected=true] span { opacity: 1; }
.use-content { background: transparent; border: 0; border-left: 1px solid #455548; border-radius: 0; padding: 6px 0 7px clamp(27px,3.5vw,52px); min-height: 0; }
.use-layout > .use-nav { grid-area: 1 / 1; }
.use-layout > .use-content { grid-area: 1 / 2; align-self: stretch; }
.use-layout > .use-content[hidden] { display: block !important; visibility: hidden; pointer-events: none; }
.use-content .kicker { font-size: 10px; color: #b3c3a6; }
.use-content h3 { max-width: 26ch; font-size: clamp(28px,2.7vw,40px); line-height: 1.13; margin-top: 19px; }
.use-content > p { margin-top: 16px; font-size: 14px; line-height: 1.76; }
.decision-record { margin: 23px 0 0; }
.decision-record > div { display: grid; grid-template-columns: 95px minmax(0,1fr); gap: 16px; padding: 13px 0; border-top: 1px solid #3c5040; }
.decision-record dt { color: #d0d8c7; font-size: 11px; font-weight: 550; }
.decision-record dd { margin: 0; color: #b8c7b9; font-size: 13px; line-height: 1.65; }
.research-feature { border-radius: 8px; overflow: hidden; }
.research-visual { min-height: 335px; padding: clamp(28px,3vw,42px); background: #e4ebdb; }
.research-visual .molecule { right: -8px; top: 10%; }
.research-visual h3 { font-size: clamp(37px,3.75vw,54px); }
.research-body { padding: clamp(26px,3.1vw,45px); }
.research-body p { font-size: 14px; line-height: 1.73; }
.research-body .status { font-size: 10px; }
.funding-line { font-size: 12px; line-height: 1.65; }
.funding-logo { border-radius: 2px; }
.team-grid { gap: clamp(28px,4vw,60px); }
.person { grid-template-columns: minmax(113px,.68fr) minmax(0,1fr); gap: clamp(17px,2vw,30px); padding-top: 23px; }
.person-visual { border-radius: 5px; aspect-ratio: .78; }
.person-info h3 { font-size: clamp(23px,2vw,30px); line-height: 1.12; }
.person-info p { line-height: 1.75; font-size: 13px; margin-top: 15px; }
.person-role { font-size: 9px; }
.strategy-review { padding-block: var(--section-space); background: #e7ecdf; }
.strategy-review .wrap { grid-template-columns: minmax(0,1.2fr) minmax(0,.8fr); gap: clamp(45px,7vw,96px); align-items: start; }
.strategy-review .text-link { margin-top: 24px; }
.strategy-review p { color: #54624d; line-height: 1.76; }
.strategy-trial { border-left: 1px solid #bbc7b0; padding: 5px 0 5px clamp(26px,3.8vw,56px); }
.strategy-trial h3 { font-size: clamp(23px,2.5vw,35px); line-height: 1.14; }
.strategy-trial p { margin-top: 13px; font-size: 14px; }
.strategy-trial .button { margin-top: 22px; background: #243b2b; }
.strategy-trial .button:hover { background: #35503c; }
.tour-evaluation { padding: clamp(42px,5vw,70px) 0; border-top: 1px solid var(--line); }
.tour-evaluation .wrap { display: flex; align-items: center; justify-content: space-between; gap: 30px; }
.tour-evaluation h2 { font-size: clamp(26px,2.6vw,38px); }
.tour-evaluation p { font-size: 15px; margin-top: 12px; }
.page-hero { padding: clamp(55px,5.5vw,86px) 0; }
.page-hero h1 { font-size: clamp(43px,5.5vw,76px); }
.page-hero .lead { max-width: 63ch; line-height: 1.78; font-size: 17px; }
.site-footer { background: #14221b; padding-block: 46px 25px; }
.footer-links { gap: clamp(32px,4vw,66px); }
.footer-links a { font-size: 12px; color: #ced8cd; }
.footer-links a:hover,.footer-bottom a:hover { color: #f7df76; }
.footer-links .kicker { font-size: 10px; }
.footer-bottom { line-height: 1.8; }
.legal-page { background: #fafbf7; }
.legal-page .page-hero { padding-block: clamp(48px,4.7vw,70px); }
.legal-page .page-hero h1 { font-size: clamp(44px,4.6vw,64px); }
.legal-page .section { padding-block: clamp(40px,5vw,67px); }
.legal-page .prose { max-width: 870px; }
.legal-page .prose section { border-top: 1px solid var(--line); padding-block: 22px 6px; margin-bottom: 30px; }
.legal-page .prose h2 { font-size: clamp(24px,2.3vw,31px); margin-bottom: 16px; }
.legal-page .prose p { max-width: 70ch; font-size: 15px; line-height: 1.8; }

/* A short, once-only reveal makes the extent of the interval legible.
   Each result and control is visible without JavaScript or animation. */
@keyframes show-interval { from { clip-path: inset(0 100% 0 0); } to { clip-path: inset(0); } }
@keyframes show-selection { from { opacity: .82; transform: translateY(3px); } to { opacity: 1; transform: none; } }
@media (prefers-reduced-motion: no-preference) {
  .finding-window .interval-measure { animation: show-interval 560ms var(--motion-ease) both; }
  .use-content:not([hidden]) { animation: show-selection 190ms var(--motion-ease); }
  .nav.is-open { animation: show-selection 160ms var(--motion-ease); }
  .ft-panel:not([hidden]) { animation: show-selection 160ms var(--motion-ease); }
  .faq[open] > p { animation: show-selection 180ms var(--motion-ease); }
}
@media (hover: hover) and (pointer: fine) {
  .return-home:hover .ui-arrow { transform: translateX(-3px); }
}
@media (max-width: 1040px) {
  :root { --rail: 35px; }
  .hero-grid { gap: 33px; }
  .hero .actions { gap: 11px; }
  .hero .button { gap: 13px; padding-inline: 14px; font-size: 12px; }
  .research-body h3 br { display: none; }
  .analysis-introduction .split { gap: 38px; }
  .person { grid-template-columns: minmax(100px,.6fr) minmax(0,1fr); }
  .report-contents > div { grid-template-columns: 85px minmax(0,1fr); }
}
@media (max-width: 900px) {
  .site-header { height: 65px; }
  .header-inner { gap: 16px; }
  .logo { width: 125px; height: 40px; }
  .menu-button { display: block; min-height: 40px; font-size: 13px; }
  .nav { display: none; position: absolute; top: 65px; right: 0; left: 0; padding: 17px var(--rail) 24px; background: #f8f8f3; border-bottom: 1px solid var(--line); box-shadow: 0 18px 35px #19261916; flex-direction: column; align-items: stretch; gap: 0; }
  .nav.is-open { display: flex; }
  .nav a:not(.button) { padding: 12px 0; font-size: 15px; border-bottom: 1px solid var(--line); }
  .nav > a:not(.button)::after { content: none; }
  .nav .button { padding: 13px 15px; margin-top: 12px; }
}
@media (max-width: 800px) {
  .hero-grid { grid-template-columns: 1fr; padding-block: 55px 43px; gap: 31px; }
  .hero-copy { max-width: 600px; }
  .hero h1 { font-size: clamp(54px,8.4vw,68px); }
  .hero-copy > p { max-width: 49ch; }
  .finding-window { max-width: 550px; justify-self: start; }
  .finding-window h2 { font-size: 41px; }
  .analysis-introduction .split { grid-template-columns: 1fr; }
  .analysis-introduction .problem-copy > p { max-width: 62ch; }
  .section-head > p { max-width: 58ch; }
  .method-foot { align-items: start; }
  .report-composition { grid-template-columns: minmax(0,1.05fr) minmax(0,.95fr); gap: 26px; }
  .report-contents > div { grid-template-columns: 1fr; gap: 3px; padding-block: 11px; }
  .report-display { padding: 23px 19px 17px; }
  .report-display figcaption { flex-wrap: wrap; }
  .use-layout { grid-template-columns: minmax(0,1fr); gap: 0; }
  .use-layout > .use-content { grid-area: 2 / 1; }
  .use-nav { gap: 5px 13px; margin-bottom: 25px; }
  .use-button { font-size: 13px; padding: 10px 0; min-height: 43px; }
  .use-content { border-left: 0; border-top: 1px solid #455548; padding: 25px 0 0; }
  .use-content > p { max-width: 61ch; }
  .research-visual { min-height: 250px; }
  .person { grid-template-columns: minmax(100px,160px) minmax(0,1fr); }
  .person-info p { max-width: 54ch; font-size: 14px; }
  .strategy-review .wrap { gap: 32px; }
  .ft-toolbar { gap: 12px; }
  .tour-evaluation .wrap { align-items: flex-start; }
}
@media (max-width: 600px) {
  .form-fields :is(input,select,textarea) { font-size: 16px; }
  :root { --rail: 22px; --section-space: 58px; }
  .hero-grid { padding-block: 45px 36px; }
  .hero h1 { font-size: clamp(48px,12.8vw,66px); }
  .hero-copy > p { font-size: 15px; line-height: 1.76; margin-top: 20px; }
  .hero .actions { margin-top: 24px; }
  .hero .button { min-height: 46px; }
  .hero-footnote { font-size: 10px; margin-top: 18px; }
  .finding-window-body { padding: 21px 21px 16px; }
  .finding-window h2 { font-size: 37px; margin-top: 17px; }
  .finding-window-bar { padding-inline: 13px; font-size: 10px; }
  .finding-context { font-size: 10px; }
  .finding-window-body > p { font-size: 12px; }
  .finding-interval p { font-size: 10px; }
  .finding-report-link { padding: 12px 21px; }
  .network-band { padding-block: 24px; }
  .network-heading { margin-bottom: 21px; }
  .challenge-item { grid-template-columns: 25px minmax(0,1fr); gap: 12px; padding-block: 20px; }
  .challenge-item p { font-size: 14px; }
  .method-grid { grid-template-columns: 1fr; gap: 0; }
  .method-card { display: grid; grid-template-columns: 58px minmax(0,1fr); gap: 4px 17px; padding: 18px 0; }
  .method-card .number { grid-row: span 2; flex-direction: column; align-items: flex-start; justify-content: flex-start; gap: 13px; }
  .method-card h3 { margin: 0; font-size: 23px; }
  .method-card h3 br { display: none; }
  .method-card p { margin-top: 4px; font-size: 14px; }
  .method-foot { margin-top: 12px; }
  .report-composition { grid-template-columns: 1fr; gap: 28px; }
  .report-contents > div { grid-template-columns: 83px minmax(0,1fr); gap: 12px; }
  .report-display { padding: 23px; }
  .report-thumbnail { width: min(100%,215px); }
  .report-display figcaption { margin-top: 20px; }
  .report-copy .report-intro { font-size: 15px; }
  .research-visual { min-height: 225px; }
  .research-visual .molecule { top: -18px; }
  .research-body { padding: 23px; }
  .replication-context { border-radius: 4px; }
  .standard-intro { font-size: 16px; }
  .rigour-grid h3 { font-size: 25px; }
  .use-nav { gap: 4px 15px; }
  .use-button { font-size: 12px; }
  .use-content h3 { font-size: 30px; }
  .decision-record > div { grid-template-columns: 77px minmax(0,1fr); gap: 10px; }
  .decision-record dd { font-size: 12px; }
  .person { grid-template-columns: minmax(94px,32%) minmax(0,1fr); gap: 18px; }
  .person-info h3 { font-size: 22px; }
  .person-info p { font-size: 13px; }
  .person-info .text-link { font-size: 12px; }
  .strategy-review .wrap { grid-template-columns: 1fr; gap: 26px; }
  .strategy-trial { border-left: 0; border-top: 1px solid #bbc7b0; padding: 24px 0 0; }
  .tour-evaluation .wrap { flex-direction: column; gap: 18px; }
  .footer-links { gap: 20px 28px; }
  .legal-page .prose section { padding-top: 18px; }
}
@media (max-width: 360px) {
  :root { --rail: 17px; }
  .finding-context { flex-direction: column; gap: 1px; }
  .network-heading .kicker { max-width: 13em; }
  .ft-toolbar { flex-wrap: wrap; }
}
@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  .button .ui-arrow,.text-link .ui-arrow,.menu-glyph i { transition: none; }
}

/* The root scroll padding already clears the sticky header. */
.sci-section, .sci-comparison, .sci-project [id], .sci-references [id] { scroll-margin-top: 1rem; }